Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouse
We previously identified Wiz in a mouse screen for epigenetic modifiers. Due to its known association with G9a/GLP, Wiz is generally considered a transcriptional repressor. Here, we provide evidence that it may also function as a transcriptional activator. Wiz levels are high in the brain, but its f...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-07-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/15082 |