Oxidative Stress-Induced Afterdepolarizations and Protein Kinase C Signaling

Oxidative Stress-Induced Afterdepolarizations and Protein Kinase C Signaling

Background: Hydrogen peroxide (H2O2)-induced oxidative stress has been demonstrated to induce afterdepolarizations and triggered activities in isolated myocytes, but the underlying mechanisms remain not fully understood. We aimed to explore whether protein kinase C (PKC) activation plays an importan...

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Bibliographic Details
Main Authors: Yu-Dong Fei, Wei Li, Jian-Wen Hou, Kai Guo, Xiao-Meng Chen, Yi-He Chen, Qian Wang, Xiao-Lei Xu, Yue-Peng Wang, Yi-Gang Li
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:International Journal of Molecular Sciences
Subjects:
oxidative stress
afterdepolarization
triggered activity
protein kinase C
arrhythmia
Online Access:http://www.mdpi.com/1422-0067/18/4/688

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http://www.mdpi.com/1422-0067/18/4/688

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