Chronic helminth infection does not exacerbate Mycobacterium tuberculosis infection.

Chronic helminth infections induce a Th2 immune shift and establish an immunoregulatory milieu. As both of these responses can suppress Th1 immunity, which is necessary for control of Mycobacterium tuberculosis (MTB) infection, we hypothesized that chronic helminth infections may exacerbate the cour...

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Bibliographic Details
Main Authors: Marc P Hübner, Kristin E Killoran, Michael Rajnik, Samuel Wilson, Kevin C Yim, Marina N Torrero, Christopher P Morris, Boris Nikonenko, Jorge C G Blanco, Val G Hemming, Edward Mitre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3529511?pdf=render