Quercetin inhibits LPS-induced macrophage migration by suppressing the iNOS/FAK/paxillin pathway and modulating the cytoskeleton

Quercetin inhibits LPS-induced macrophage migration by suppressing the iNOS/FAK/paxillin pathway and modulating the cytoskeleton

The natural flavonoid quercetin has antioxidant, anti-inflammatory, and anticancer effects. We investigated the effect of quercetin on lipopolysaccharide (LPS)-induced macrophage migration. Quercetin significantly attenuated LPS-induced inducible nitric oxide synthase (iNOS)-derived nitric oxide (NO...

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Bibliographic Details
Main Authors: Shuna Cui, Qingqing Wu, Juan Wang, Min Li, Jing Qian, Shihua Li
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Cell Adhesion & Migration
Subjects:
quercetin
macrophage
migration
inos/fak-paxillin pathway
Online Access:http://dx.doi.org/10.1080/19336918.2018.1486142

Internet

http://dx.doi.org/10.1080/19336918.2018.1486142

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