MFAP5 facilitates the aggressiveness of intrahepatic Cholangiocarcinoma by activating the Notch1 signaling pathway

MFAP5 facilitates the aggressiveness of intrahepatic Cholangiocarcinoma by activating the Notch1 signaling pathway

Abstract Background Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver cancer. The dismal outcome of ICC patients is due to lack of early diagnosis, the aggressive biological behavior of ICC and the lack of effective therapeutic options. Early diagnosis and prognosis of IC...

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Main Authors: Jian-Hui Li, Xiao-Xu Zhu, Fu-Xi Li, Chen-Song Huang, Xi-Tai Huang, Jie-Qin Wang, Zhuo-Xing Gao, Shi-Jin Li, Qiong-Cong Xu, Wei Zhao, Xiao-Yu Yin
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
MFAP5
Intrahepatic cholangiocarcinoma
Cancer biomarkers
NOTCH
Cell cycle arrest
Online Access:http://link.springer.com/article/10.1186/s13046-019-1477-4

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http://link.springer.com/article/10.1186/s13046-019-1477-4

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