Antinociceptive tolerance to NSAIDs in the agranular insular cortex is mediated by opioid mechanism

Natia Pirkulashvili,1 Nana Tsiklauri,1 Marina Nebieridze,2 Merab G Tsagareli1 1Laboratory of Pain and Analgesia, 2Laboratory of Brain Metabolism, Beritashvili Center for Experimental Biomedicine, Tbilisi, Georgia Abstract: Several lines of investigations have shown that in some brain areas, in parti...

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Bibliographic Details
Main Authors: Pirkulashvili N, Tsiklauri N, Nebieridze M, Tsagareli MG
Format: Article
Language:English
Published: Dove Medical Press 2017-07-01
Series:Journal of Pain Research
Subjects:
Online Access:https://www.dovepress.com/antinociceptive-tolerance-to-nsaids-in-the-agranular-insular-cortex-is-peer-reviewed-article-JPR