Derrone induces autophagic cell death through induction of ROS and ERK in A549 cells.

We studied the effect of derrone (DR), one of the major compounds of unripe fruits of Cudrania tricuspidata, on cancer cell death. DR inhibited cell growth of various cancer cells, and that was partially associated with apoptosis in A549 cells. DR showed the autophagic features, such as the conversi...

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Bibliographic Details
Main Authors: Myung-Ji Kang, Soo-Yeon Kim, Eun-Bin Kwon, Yang Hee Jo, Mi Kyeong Lee, Hyun-Sun Lee, Dong-Oh Moon, Mun-Ock Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218659