Recombinant CsHscB of carcinogenic liver fluke Clonorchis sinensis induces IL-10 production by binding with TLR2.

<h4>Background</h4>Clonorchis sinensis, a fluke dwelling in the intrahepatic bile ducts causes clonorchiasis, which affect about 15 million people wide-distributed in eastern Asia. During C. sinensis infection, worm-host interaction results in activation of patterns recognition receptors...

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Main Authors: Chao Yan, Fan Fang, Yu-Zhao Zhang, Xin Dong, Jing Wu, Hai-Liang Liu, Chun-Yang Fan, Stephane Koda, Bei-Bei Zhang, Qian Yu, Liang Wang, Yu-Gang Wang, Jia-Xu Chen, Kui-Yang Zheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008643