The Relevance of the UPS in Fatty Liver Graft Preservation: A New Approach for IGL-1 and HTK Solutions

The Relevance of the UPS in Fatty Liver Graft Preservation: A New Approach for IGL-1 and HTK Solutions

The 26S proteasome is the central proteolytic machinery of the ubiquitin proteasome system (UPS), which is involved in the degradation of ubiquitinated protein substrates. Recently, UPS inhibition has been shown to be a key factor in fatty liver graft preservation during organ cold storage using Uni...

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Bibliographic Details
Main Authors: Arnau Panisello-Roselló, Eva Verde, Mohamed Amine Zaouali, Marta Flores, Norma Alva, Alexandre Lopez, Emma Folch-Puy, Teresa Carbonell, Georgina Hotter, René Adam, Joan Roselló-Catafau
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:International Journal of Molecular Sciences
Subjects:
ubiquitin proteasome system
cold ischemic injury
fatty liver preservation
IGL-1
HTK
ATP
AMPK and nitric oxide
Online Access:https://www.mdpi.com/1422-0067/18/11/2287

Internet

https://www.mdpi.com/1422-0067/18/11/2287

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