Optimization of TGF-β1-transduced chondrocytes for cartilage regeneration in a 3D printed knee joint model.

A cell therapy product of transforming growth factor (TGF)-β1-transduced chondrocytes has been commercialized to treat osteoarthritis of the knee via intra-articular injection. The need for arthroscopic application of the cells to simultaneously treat intra-articular pathologies of knee osteoarthrit...

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Bibliographic Details
Main Authors: Jiyong Ahn, Seon Ae Kim, Ki Won Kim, Joon Hyuck Oh, Seok Jung Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217601