miR-9-5p is involved in the rescue of stress-dependent dendritic shortening of hippocampal pyramidal neurons induced by acute antidepressant treatment with ketamine

miR-9-5p is involved in the rescue of stress-dependent dendritic shortening of hippocampal pyramidal neurons induced by acute antidepressant treatment with ketamine

Converging clinical and preclinical evidence demonstrates that depressive phenotypes are associated with synaptic dysfunction and dendritic simplification in cortico-limbic glutamatergic areas. On the other hand, the rapid antidepressant effect of acute ketamine is consistently reported to occur tog...

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Bibliographic Details
Main Authors: Jessica Mingardi, Luca La Via, Paolo Tornese, Giulia Carini, Kalevi Trontti, Mara Seguini, Daniela Tardito, Federica Bono, Chiara Fiorentini, Leonardo Elia, Iiris Hovatta, Maurizio Popoli, Laura Musazzi, Alessandro Barbon
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Neurobiology of Stress
Subjects:
miR-9-5p
Stress
CORT
Dendrite morphology
Ketamine
REST
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289521000898

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http://www.sciencedirect.com/science/article/pii/S2352289521000898

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