Connecting Alzheimer’s Disease With Diabetes Mellitus Through Amyloidogenic Evolvability

Type 2 diabetes mellitus (T2DM) has been clearlylinked to oxidative stress and amylin amyloidosis in pancreatic β-cells. Yet despite extensive investigation, the biological significance of this is not fully understood. Recently, we proposed that Alzheimer’s disease (AD)-relevant amyloidogenic protei...

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Bibliographic Details
Main Authors: Gilbert Ho, Yoshiki Takamatsu, Ryoko Wada, Shuei Sugama, Masaaki Waragai, Takato Takenouchi, Eliezer Masliah, Makoto Hashimoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2020.576192/full