High-throughput analysis using non-depletive SPME: challenges and applications to the determination of free and total concentrations in small sample volumes

Abstract In vitro high-throughput non-depletive quantitation of chemicals in biofluids is of growing interest in many areas. Some of the challenges facing researchers include the limited volume of biofluids, rapid and high-throughput sampling requirements, and the lack of reliable methods. Coupled t...

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Bibliographic Details
Main Authors: Ezel Boyacı, Barbara Bojko, Nathaly Reyes-Garcés, Justen J. Poole, Germán Augusto Gómez-Ríos, Alexandre Teixeira, Beate Nicol, Janusz Pawliszyn
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-19313-1