High-throughput analysis using non-depletive SPME: challenges and applications to the determination of free and total concentrations in small sample volumes
Abstract In vitro high-throughput non-depletive quantitation of chemicals in biofluids is of growing interest in many areas. Some of the challenges facing researchers include the limited volume of biofluids, rapid and high-throughput sampling requirements, and the lack of reliable methods. Coupled t...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-01-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-018-19313-1 |