Evaluation of skin phototoxicity of transdermally administered pharmaceuticals in Sprague-Dawley rats

Abstract Some drugs cause phototoxicity in humans when exposed to light, thus there is a need for an in vivo phototoxicity test to evaluate them. However, an in vivo phototoxicity test method to evaluate this has not been established. This study aimed to establish an in vivo phototoxicity test metho...

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Bibliographic Details
Main Authors: Nam Hee Youn, Eun Ji Kim, Jung-Sun Yi, Joo Hwan Kim, Ye-Jin Cho, Ki Taek Nam, Ki Sook Park, Jong Kwon Lee
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Laboratory Animal Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s42826-020-00074-w