Drug repositioning using drug-disease vectors based on an integrated network

Abstract Background Diverse interactions occur between biomolecules, such as activation, inhibition, expression, or repression. However, previous network-based studies of drug repositioning have employed interaction on the binary protein-protein interaction (PPI) network without considering the char...

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Bibliographic Details
Main Authors: Taekeon Lee, Youngmi Yoon
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2490-x