Preclinical Testing of CAR T Cells in a Patient-Derived Xenograft Model of Glioblastoma

Summary: Glioblastoma (GBM) is the most common malignant adult brain tumor that is resistant to the standard care therapy. Advances in chimeric antigen receptor (CAR) T cell therapies have spurred renewed interest in developing CAR T cell therapies to target chemoradiotherapy-resistant brain tumor-i...

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Bibliographic Details
Main Authors: Nazanin Tatari, William T. Maich, Sabra K. Salim, Dillon Mckenna, Chitra Venugopal, Sheila Singh
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166720301611