HDAC3 deteriorates colorectal cancer progression via microRNA-296-3p/TGIF1/TGFβ axis

HDAC3 deteriorates colorectal cancer progression via microRNA-296-3p/TGIF1/TGFβ axis

Abstract Background The mechanism of histone deacetylase 3 (HDAC3) in colorectal cancer (CRC) has already been discussed. However, the feedback loop of HDAC3/microRNA (miR)-296-3p and transforming growth factor β-induced factor 1 (TGIF1) in CRC has not been explained clearly. Thus, the mainstay of t...

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Bibliographic Details
Main Authors: Jinxiao Li, Man Hu, Na Liu, Huarong Li, Zhaomin Yu, Qian Yan, Minfeng Zhou, Yayuan Wang, Yanjuan Song, Guangtao Pan, Fengxia Liang, Rui Chen
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Colorectal cancer
Histone deacetylase 3
MicroRNA-296-3p
Thymine-guanine-interacting factor 1
Transforming growth factor β signaling pathway
Invasion
Online Access:http://link.springer.com/article/10.1186/s13046-020-01720-w

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http://link.springer.com/article/10.1186/s13046-020-01720-w

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