High Mobility Group Box 1 Contributes to the Acute Rejection of Liver Allografts by Activating Dendritic Cells

High Mobility Group Box 1 Contributes to the Acute Rejection of Liver Allografts by Activating Dendritic Cells

Acute rejection induced by the recognition of donor alloantigens by recipient T cells leads to graft failure in liver transplant recipients. The role of high mobility group box 1 (HMGB1), an inflammatory mediator, in the acute allograft rejection of liver transplants is unknown. Here, rat orthotopic...

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Bibliographic Details
Main Authors: Yi Chen, Wenmin Zhang, Hui Bao, Wubing He, Lihong Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
glycyrrhizic acid
HMGB1
acute rejection
liver transplantation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.679398/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.679398/full

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