She1 affects dynein through direct interactions with the microtubule and the dynein microtubule-binding domain
Dynein is a microtubule motor the motility of which is affected by the microtubule-associated protein She1. Here, the authors show that She1 alters dynein stepping behavior and increases its microtubule affinity through simultaneous interactions with the microtubule and dynein microtubule binding do...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-12-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-02004-2 |