Structural and functional insights into the catalytic inactivity of the major fraction of buffalo milk xanthine oxidoreductase.

BACKGROUND: Xanthine oxidoreductase (XOR) existing in two interconvertible forms, xanthine dehydrogenase (XDH) and xanthine oxidase (XO), catabolises xanthine to uric acid that is further broken down to antioxidative agent allantoin. XOR also produces free radicals serving as second messenger and mi...

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Bibliographic Details
Main Authors: Kaustubh S Gadave, Santanu Panda, Surender Singh, Shalini Kalra, Dhruba Malakar, Ashok K Mohanty, Jai K Kaushik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3909206?pdf=render