Serum Neurofilament Light and GFAP Are Associated With Disease Severity in Inflammatory Disorders With Aquaporin-4 or Myelin Oligodendrocyte Glycoprotein Antibodies

Serum Neurofilament Light and GFAP Are Associated With Disease Severity in Inflammatory Disorders With Aquaporin-4 or Myelin Oligodendrocyte Glycoprotein Antibodies

Objective: To evaluate the potential of serum neurofilament light (sNfL) and serum glial fibrillary acidic protein (sGFAP) as disease biomarkers in neuromyelitis optica spectrum disorder (NMOSD) with aquaporin-4 antibody (AQP4-ab) or myelin oligodendrocyte glycoprotein-antibody-associated disease (M...

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Main Authors: Xuechun Chang, Wenjuan Huang, Liang Wang, Jingzi ZhangBao, Lei Zhou, Chuanzhen Lu, Min Wang, Jian Yu, Haiqing Li, Yuxin Li, Chongbo Zhao, Jiahong Lu, Chao Quan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
neurofilament light
glial fibrillary acidic protein
aquaporin-4
myelin oligodendrocyte glycoprotein
neuromyelitis optica spectrum disorder
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.647618/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.647618/full

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