Mesoscale phase separation of chromatin in the nucleus

Intact-organism imaging of Drosophila larvae reveals and quantifies chromatin-aqueous phase separation. The chromatin can be organized near the lamina layer of the nuclear envelope, conventionally fill the nucleus, be organized centrally, or as a wetting droplet. These transitions are controlled by...

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Bibliographic Details
Main Authors: Gaurav Bajpai, Daria Amiad Pavlov, Dana Lorber, Talila Volk, Samuel Safran
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/63976