A parameter for IL-10 and TGF-ß mediated regulation of HIV-1 specific T cell activation provides novel information and relates to progression markers.

A parameter for IL-10 and TGF-ß mediated regulation of HIV-1 specific T cell activation provides novel information and relates to progression markers.

HIV replication is only partially controlled by HIV-specific activated effector T cells in chronic HIV infection and strategies are warranted to improve their efficacy. Chronic T cell activation is generally accompanied by regulation of antigen-specific T cell responses which may impair an effective...

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Bibliographic Details
Main Authors: Andreas Lind, Kristin Brekke, Frank Olav Pettersen, Tom Eirik Mollnes, Marius Trøseid, Dag Kvale
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3887102?pdf=render

Internet

http://europepmc.org/articles/PMC3887102?pdf=render

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