Using sequence-specific chemical and structural properties of DNA to predict transcription factor binding sites.

Using sequence-specific chemical and structural properties of DNA to predict transcription factor binding sites.

An important step in understanding gene regulation is to identify the DNA binding sites recognized by each transcription factor (TF). Conventional approaches to prediction of TF binding sites involve the definition of consensus sequences or position-specific weight matrices and rely on statistical a...

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Bibliographic Details
Main Authors: Amy L Bauer, William S Hlavacek, Pat J Unkefer, Fangping Mu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2987836?pdf=render

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http://europepmc.org/articles/PMC2987836?pdf=render

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