Unique role of NADPH oxidase 5 in oxidative stress in human renal proximal tubule cells

NADPH oxidases are the major sources of reactive oxygen species in cardiovascular, neural, and kidney cells. The NADPH oxidase 5 (NOX5) gene is present in humans but not rodents. Because Nox isoforms in renal proximal tubules (RPTs) are involved in the pathogenesis of hypertension, we tested the hy...

Full description

Bibliographic Details
Main Authors: Peiying Yu, Weixing Han, Van Anthony M. Villar, Yu Yang, Quansheng Lu, Hewang Lee, Fengmin Li, Mark T. Quinn, John J. Gildea, Robin A. Felder, Pedro A. Jose
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Redox Biology
Subjects:
ROS
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231714000354