B cells play a cooperative role via CD40L–CD40 interaction in T cell-mediated experimental autoimmune neuritis in Lewis rats

B cells play a cooperative role via CD40L–CD40 interaction in T cell-mediated experimental autoimmune neuritis in Lewis rats

The expression of co-stimulatory molecules CD40 and CD40L was examined over the course of experimental autoimmune neuritis (EAN) induced in Lewis rats by immunization with bovine peripheral nerve myelin. In draining lymph nodes, highest level of CD40L expression was seen on day 7 post immunization (...

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Bibliographic Details
Main Authors: Wei Zhu, Eilhard Mix, Tao Jin, Abdu Adem, Jie Zhu
Format: Article
Language:English
Published: Elsevier 2007-03-01
Series:Neurobiology of Disease
Subjects:
Experimental autoimmune neuritis
B cell
T cell
CD40/CD40L
Co-stimulatory molecules
Guillain–Barré syndrome
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106003007

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http://www.sciencedirect.com/science/article/pii/S0969996106003007

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