Protein Palmitoylation Regulates Cell Survival by Modulating XBP1 Activity in Glioblastoma Multiforme

Protein Palmitoylation Regulates Cell Survival by Modulating XBP1 Activity in Glioblastoma Multiforme

Glioblastoma multiforme (GBM) almost invariably acquires an invasive phenotype, resulting in limited therapeutic options. Protein palmitoylation markedly affects tumorigenesis and malignant progression in GBM. The role of protein palmitoylation in GBM, however, has not been systematically reported....

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Bibliographic Details
Main Authors: Xueran Chen, Hao Li, Xiaoqing Fan, Chenggang Zhao, Kaiqin Ye, Zhiyang Zhao, Lizhu Hu, Huihui Ma, Hongzhi Wang, Zhiyou Fang
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Oncolytics
Subjects:
protein palmitoylation
endoplasmic reticulum stress response
X-box binding protein 1
palmitoyltransferases
glioblastoma multiforme
Online Access:http://www.sciencedirect.com/science/article/pii/S237277052030070X

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http://www.sciencedirect.com/science/article/pii/S237277052030070X

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