Dipeptidyl peptidase 4 promotes peritoneal fibrosis and its inhibitions prevent failure of peritoneal dialysis

Li et al. show that dipeptidyl peptidase 4 (DPP4) promotes peritoneal fibrosis whereas the inhibition of DPP4 protects the patients from failure of peritoneal dialysis. This study provides mechanistic insights into the effects of DPP4 on peritoneal fibrosis and the translational potential of these e...

Full description

Bibliographic Details
Main Authors: Yi-Chen Li, Pei-Hsun Sung, Yao-Hsu Yang, John Y. Chiang, Hon-Kan Yip, Chih‐Chao Yang
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01652-x