High drug payload curcumin nanosuspensions stabilized by mPEG-DSPE and SPC: in vitro and in vivo evaluation

High drug payload curcumin nanosuspensions stabilized by mPEG-DSPE and SPC: in vitro and in vivo evaluation

Context: Curcumin (CUR) is a promising drug candidate based on its broad bioactivities and good antitumor effect, but the application of CUR is potentially restricted because of its poor solubility and bioavailability. Objective: This study aims at developing a simple and effective drug delivery sys...

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Bibliographic Details
Main Authors: Jingyi Hong, Yingying Liu, Yao Xiao, Xiaofeng Yang, Wenjing Su, Mingzhu Zhang, Yonghong Liao, Haixue Kuang, Xiangtao Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Drug Delivery
Subjects:
curcumin
nanosuspensions
high drug payload
pharmacokinetics
biodistribution
antitumor efficacy
Online Access:http://dx.doi.org/10.1080/10717544.2016.1233589

Internet

http://dx.doi.org/10.1080/10717544.2016.1233589

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