Mutational sources of trans-regulatory variation affecting gene expression in Saccharomyces cerevisiae

Mutational sources of trans-regulatory variation affecting gene expression in Saccharomyces cerevisiae

Heritable variation in a gene’s expression arises from mutations impacting cis- and trans-acting components of its regulatory network. Here, we investigate how trans-regulatory mutations are distributed within the genome and within a gene regulatory network by identifying and characterizing 69 mutat...

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Bibliographic Details
Main Authors: Fabien Duveau, Petra Vande Zande, Brian PH Metzger, Crisandra J Diaz, Elizabeth A Walker, Stephen Tryban, Mohammad A Siddiq, Bing Yang, Patricia J Wittkopp
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-08-01
Series:eLife
Subjects:
gene regulation
bulk segregant analysis
TDH3
RAP1
GCR1
eQTL
Online Access:https://elifesciences.org/articles/67806

Internet

https://elifesciences.org/articles/67806

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