Synthetic Resveratrol Analogue, 3,3',4,4',5,5'-Hexahydroxy-trans-Stilbene, Accelerates Senescence in Peritoneal Mesothelium and Promotes Senescence-Dependent Growth of Gastrointestinal Cancers

Synthetic Resveratrol Analogue, 3,3',4,4',5,5'-Hexahydroxy-trans-Stilbene, Accelerates Senescence in Peritoneal Mesothelium and Promotes Senescence-Dependent Growth of Gastrointestinal Cancers

3,3',4,4',5,5'-Hexahydroxy-trans-stilbene (M8) is a synthetic resveratrol derivative, advertised as a candidate drug highly effective against numerous malignancies. Because multiple tumors prone to M8 frequently metastasize into the peritoneal cavity, this study was aimed...

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Bibliographic Details
Main Authors: Krzysztof Książek, Marcin Wierzchowski, Katarzyna Piwocka, Patrycja Sosińska, Justyna Mikuła-Pietrasik
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:International Journal of Molecular Sciences
Subjects:
cancer metastases
mesothelial cells
peritoneal cavity
replicative senescence
stilbenes
Online Access:http://www.mdpi.com/1422-0067/14/11/22483

Internet

http://www.mdpi.com/1422-0067/14/11/22483

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