Upregulation of Beta4 subunit of BKCa channels in the anterior cingulate cortex contributes to mechanical allodynia associated anxiety-like behaviors

Upregulation of Beta4 subunit of BKCa channels in the anterior cingulate cortex contributes to mechanical allodynia associated anxiety-like behaviors

Abstract The anterior cingulate cortex (ACC) serves as a critical hub for the anxiety and pain perception. The large-conductance Ca2+-activated potassium channels, or BKCa channels, are ubiquitously expressed throughout the central nervous system including the cingulate cortex. However, what changes...

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Bibliographic Details
Main Authors: Huan Zhao, Qian Xue, Cong Li, Qingchuan Wang, Shichao Han, Yongsheng Zhou, Tao Yang, Yingli Xie, Hao Fu, Changbo Lu, Fancheng Meng, Ming Zhang, Yan Zhang, Xianglong Wu, Shengxi Wu, Min Zhuo, Hui Xu
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Molecular Brain
Subjects:
Anterior cingulate cortex
Anxiety
Large-conductance Ca2+-activated potassium channel
Excitability
Synaptic transmission
Online Access:http://link.springer.com/article/10.1186/s13041-020-0555-z

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http://link.springer.com/article/10.1186/s13041-020-0555-z

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