Pax4 Expression does not Transduce Pancreatic Alpha Cells to Beta Cells

Pax4 Expression does not Transduce Pancreatic Alpha Cells to Beta Cells

Background/Aims: The lack of available beta cells greatly limits the use of beta cell transplantation as a therapy for diabetes. Thus, generation of beta cells from other sources is substantially required. Pax4 has been shown to induce reprograming of alpha cells into beta cells during embryogenesis...

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Bibliographic Details
Main Authors: Ling Chen, Jing Zhang, Zhuo Zhang, Yaping Chu, Bing Song, Wang Cai
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Beta cells
Pax4
Alpha cells
Alpha-to-beta cell reprogramming
Diabetes
Online Access:http://www.karger.com/Article/FullText/430146

Internet

http://www.karger.com/Article/FullText/430146

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