Limb ischemic preconditioning ameliorates renal microcirculation through activation of PI3K/Akt/eNOS signaling pathway after acute kidney injury

Limb ischemic preconditioning ameliorates renal microcirculation through activation of PI3K/Akt/eNOS signaling pathway after acute kidney injury

Abstract Purpose Contrast-induced acute kidney injury (CI-AKI) resulting from administration of iodinated contrast media (CM) is the third leading cause of hospital-acquired acute kidney injury and is associated with substantial morbidity and mortality. Deteriorated renal microcirculation plays an i...

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Bibliographic Details
Main Authors: Cheng Chen, Li Sun, Wanfen Zhang, Yushang Tang, Xiaoping Li, Ran Jing, Tongqiang Liu
Format: Article
Language:English
Published: BMC 2020-03-01
Series:European Journal of Medical Research
Subjects:
Acute kidney injury
Limb ischemic preconditioning
PI3K
Akt/eNOS
Wortmannin
Online Access:http://link.springer.com/article/10.1186/s40001-020-00407-4

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http://link.springer.com/article/10.1186/s40001-020-00407-4

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