Protein defence systems against the lantibiotic nisin: Function of the immunity protein NisI and the resistance protein NSR

Lantibiotics are potential alternatives to antibiotics because of their broad-range killing spectrum. The producer strain is immune against its own synthesized lantibiotic via the expression of two proteins LanI and LanFEG. Recently, gene operons are found in mainly human pathogenic strains, which c...

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Bibliographic Details
Main Authors: Sakshi eKhosa, Marcel eLagedroste, Sander Hj Smits
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00504/full