Genomic and Clinical Correlates of Adrenocortical Carcinoma in an Adult Patient with Li-Fraumeni Syndrome: A Case Report

Li-Fraumeni Syndrome (LFS) is defined by germline mutations of the p53 tumour suppressor gene. Adrenocortical carcinoma (ACC) is a rare aggressive malignancy that is commonly associated with LFS. Most LFS-linked ACC cases occur in children, and limited research has been dedicated to the clinical out...

Full description

Bibliographic Details
Main Authors: Suraya Bondy, Camilla Tajzler, Sebastien J. Hotte, Anil Kapoor, Kevin Zbuk, Aly-Khan A. Lalani
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Current Oncology
Subjects:
Online Access:https://www.mdpi.com/1718-7729/28/1/25