Mechanisms of antidepressant resistance

Depression is one of the most frequent and severe mental disorder. Since the discovery of antidepressant properties of the imipramine and then after of other tricyclic compounds, several classes of psychotropic drugs have shown be effective in treating major depressive disorder. However, there is a...

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Bibliographic Details
Main Authors: Wissam eEl Hage, Samuel eLeman, Vincent eCamus, Catherine eBelzung
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00146/full