Effect of phospholipase A2 inhibitors during infection caused by Leishmania (Leishmania) amazonensis

Abstract Background Lipid metabolites play an important role in parasite differentiation and virulence. Studies have revealed that Leishmania sp. uses prostaglandins to evade innate barriers, thus enabling the parasites to survive inside immune cells. Despite the role of the enzyme Phospholipase A2...

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Bibliographic Details
Main Authors: Maria L. A. C. Bordon, Márcia D. Laurenti, Susan Pereira Ribeiro, Marcos H. Toyama, Daniela de O. Toyama, Luiz Felipe D. Passero
Format: Article
Language:English
Published: SciELO 2018-08-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40409-018-0156-9