Activation of the NRF2 pathway in Keap1-knockdown mice attenuates progression of age-related hearing loss
Abstract Age-related hearing loss (AHL) is a progressive sensorineural hearing loss in elderly people. Although no prevention or treatments have been established for AHL, recent studies have demonstrated that oxidative stress is closely related to pathogenesis of AHL, suggesting that suppression of...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-12-01
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Series: | npj Aging and Mechanisms of Disease |
Online Access: | https://doi.org/10.1038/s41514-020-00053-4 |