Modified enzyme multiplied immunoassay technique of methotrexate assay to improve sensitivity and reduce cost

Modified enzyme multiplied immunoassay technique of methotrexate assay to improve sensitivity and reduce cost

Abstract Background Methotrexate is an important component in many chemotherapy protocols. The blood concentration of Methotrexate is used to determine the regimen of folinic acid. However, the lower limit of Siemens assay kit is 0.30 μmol/L in China. This study extended the limit from 0.3 to 0.05 μ...

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Bibliographic Details
Main Authors: Xiaoping Shi, Hui Gao, Zhong Li, Jinghua Li, Yang Liu, Lujuan Li, Qi Zhang
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Pharmacology and Toxicology
Subjects:
Methotrexate
Enzyme multiplied immunoassay technique
Sensitivity
Cost reduction
Online Access:http://link.springer.com/article/10.1186/s40360-018-0283-5

Internet

http://link.springer.com/article/10.1186/s40360-018-0283-5

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