Tetramethylpyrazine potentiates arsenic trioxide activity against HL-60 cell lines

The objective of this study was to evaluate the effects of tetramethylpyrazine (TMP) in combination with arsenic trioxide (As2O3) on the proliferation and differentiation of HL-60 cells. The HL-60 cells were treated with 300 µg/mL TMP, 0.5 µM As2O3, and 300 µg/mL TMP combined with 0.5 µM As2O3, resp...

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Bibliographic Details
Main Authors: Yuni Wu, Youhua Xu, Yali Shen, Cuicui Wang, Gaili Guo, Tiantian Hu
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000300002