Epitope mapping of antibodies to alpha-synuclein in LRRK2 mutation carriers, idiopathic Parkinson disease patients and healthy controls.

Epitope mapping of antibodies to alpha-synuclein in LRRK2 mutation carriers, idiopathic Parkinson disease patients and healthy controls.

Alpha-synuclein (Snca) plays a major role in Parkinson Disease (PD). Circulating anti-Snca antibodies have been described in PD patients and healthy controls, but they have been poorly characterized. This study was designed to assess the prevalence of anti-Snca reactivity in human subjects carrying...

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Bibliographic Details
Main Authors: Beatriz eAlvarez-Castelao, Ana eGorostidi, Javier eRuiz-Martinez, Adolfo eLópez de Munain, Jose G Castaño
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
alpha-Synuclein
Epitope Mapping
Parkinson Disease
ELISA
human antibodies
immunoblot
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00169/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00169/full

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