Prion Disease and the Innate Immune System

Prion diseases or transmissible spongiform encephalopathies are a unique category of infectious protein-misfolding neurodegenerative disorders. Hypothesized to be caused by misfolding of the cellular prion protein these disorders possess an infectious quality that thrives in immune-competent hosts....

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Bibliographic Details
Main Authors: Barry M. Bradford, Neil A. Mabbott
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/4/12/3389