Genetic variation in surfactant protein-A2 alters responses to ozone.

<h4>Background</h4>Increased exposure to Ozone (O3) is associated with adverse health effects in individuals afflicted with respiratory diseases. Surfactant protein-A (SP-A), encoded by SP-A1 and SP-A2, is the largest protein component in pulmonary surfactant and is functionally impaired...

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Bibliographic Details
Main Authors: William P Pederson, Jaime M Cyphert-Daly, Robert M Tighe, Loretta G Que, Julie G Ledford
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0247504