FGF21 Serum Levels in the Early Second Trimester Are Positively Correlated With the Risk of Subsequent Gestational Diabetes Mellitus: A Propensity-Matched Nested Case-Control Study

FGF21 Serum Levels in the Early Second Trimester Are Positively Correlated With the Risk of Subsequent Gestational Diabetes Mellitus: A Propensity-Matched Nested Case-Control Study

BackgroundAs an important endocrine hormone regulating glucose metabolism, fibroblast growth factor 21 (FGF21) is increased in individuals with gestational diabetes mellitus (GDM) after 24 gestational weeks. However, it is unknown whether the increase in FGF21 precedes the diagnosis of GDM.MethodsIn...

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Bibliographic Details
Main Authors: Zhiheng Wang, Min Yuan, Chengjie Xu, Yang Zhang, Chunmei Ying, Xirong Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Endocrinology
Subjects:
FGF21
gestational diabetes mellitus (GDM)
nested case-control study
propensity score matching (PSM)
early second trimester
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.630287/full

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https://www.frontiersin.org/articles/10.3389/fendo.2021.630287/full

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