π-π-Stacked Poly(ε-caprolactone)-<i>b</i>-poly(ethylene glycol) Micelles Loaded with a Photosensitizer for Photodynamic Therapy

π-π-Stacked Poly(ε-caprolactone)-<i>b</i>-poly(ethylene glycol) Micelles Loaded with a Photosensitizer for Photodynamic Therapy

To improve the in vivo stability of poly(-caprolactone)-b-poly(ethylene glycol) (PCL-PEG)-based micelles and cargo retention by π-π stacking interactions, pendant aromatic rings were introduced by copolymerization of -caprolactone with benzyl 5-methyl-2-oxo-1,3-dioxane-5-carboxylate (TMC-Bz). It w...

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Bibliographic Details
Main Authors: Yanna Liu, Marcel H.A.M. Fens, Bo Lou, Nicky C.H. van Kronenburg, Roel F.M. Maas-Bakker, Robbert J. Kok, Sabrina Oliveira, Wim E. Hennink, Cornelus F. van Nostrum
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
polymer micelles
photodynamic therapy
in vitro release
circulation kinetics
biodistribution
Online Access:https://www.mdpi.com/1999-4923/12/4/338

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https://www.mdpi.com/1999-4923/12/4/338

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