How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion

One approach to experimental science involves creating hypotheses, then testing them by varying one or more independent variables and assessing the effects of this variation on the processes of interest. We use this strategy to compare the intellectual status and available evidence for two models or...

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Bibliographic Details
Main Authors: Douglas Bruce Kell, Stephen George Oliver
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00231/full