Monoclonal antibodies reveal novel localization of SPAG11E in spermatozoa and the antifertility potential of SPAG11E motifs

Objective: SPAG11E is the first β-defensin that has been reported to activate Ca2+ uptake and sperm motility. However, the exact subcellular localization and interaction of SPAG11E with sperm remain controversial because of the lack of qualified antibody tools. SPAG11E is also a potential male antif...

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Bibliographic Details
Main Authors: Zhi-Kai Wang, Yi-Ting Yang, Xin-Yu Chen, Shuang-Gang Hu, Ping Zhu, Wan-Xiang Xu, Li Ma, He-Guo Yu, Hua Diao, Yong-Lian Zhang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Reproductive and Developmental Medicine
Subjects:
Online Access:http://www.repdevmed.org/article.asp?issn=2096-2924;year=2018;volume=2;issue=4;spage=191;epage=200;aulast=Wang