DWI and complex brain network analysis predicts vascular cognitive impairment in spontaneous hypertensive rats undergoing executive function tests

The identification of biomarkers of vascular cognitive impairment is urgent for its early diagnosis. The aim of this study was to detect and monitor changes in brain structure and connectivity, and to correlate them with the decline in executive function. We examined the feasibility of early diagnos...

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Bibliographic Details
Main Authors: Xavier eLópez-Gil, Ivan eAmat-Roldan, Raúl eTudela, Anna eCastañé, Alberto ePrats-Galino, Anna M Planas, Tracy D Farr, Guadalupe eSoria
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
DTI
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00167/full