PROP1 and CTNNB1 expression in adamantinomatous craniopharyngiomas with or without β-catenin mutations

PROP1 and CTNNB1 expression in adamantinomatous craniopharyngiomas with or without β-catenin mutations

INTRODUCTION: Activating mutations in exon 3 of the β-catenin gene are involved in the pathogenesis of adamantinomatous craniopharyngiomas. Recently, the interaction between β-catenin and PROP1 has been shown to be responsible for pituitary cell lineage determination. We hypothesiz...

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Bibliographic Details
Main Authors: Carolina M.G Cani, Hamilton Matushita, Luciani R. S Carvalho, Ibere C Soares, Luciana P Brito, Madson Q Almeida, Berenice B Mendonça
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2011-01-01
Series:Clinics
Subjects:
Sellar tumor
Real-time PCR
WNT pathway
Gene expression
Pituitary
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011001100001

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011001100001

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